It's a bad idea because theoretically lead to overflow error and possibly will be reset to defaults (Max number here is some of these: 2147483647, 429496729 depending of var. type engine uses).
Edit: I checked this. If you, e.g., set such big value on "z_health" Cvar, it automatically cast to -2147483648 (mean, all bits = 1 in signed int), cause Zombie die at the spawn moment.
The same issues is highly likely will break another CVars.
Okay then. I'll set it to your maximum values just to make sure. I have tested my value it didn't break my game and also no bots teleport activity.